Sunday, December 29, 2013

Houston, we have lift-off

Thanks to a huge influx from Richard's Christmas wish the project goal is met and the funds are now released. I want to thank everyone that contributed and wish you all a very happy and successful new year.

In fact, today I ordered up the biome sample kits for us all. They take 2-3 weeks to arrive, which works well as we're out of town on an extended winter vacation visiting friends and family. We'll be returning home next week, so will have a few weeks on our usual home diet before gathering the "before" sample.

Next is determining what additional testing we can accomplish with the over-funding we've received. There's definitely enough for a BG meter and a fair amount of test strips. I'm a little curious how a "normal" non-diabetic person's BG cycles over the course of a day and in response to various meals. Other than that, I'm not really sure. If you have any suggestions please feel free to leave a comment. This is crowd-source science after all.

In any case, again to all the contributors, I thank you. Let's hope this is the first in a long series of interesting crowd-source science to come.

3 comments:

  1. Hi, Allen,

    if you have the funds, I would be very interested in the before and after levels of 1) the fat profile, 2) Vitamin D, Vitamin B12 and homocistein blood levels 3) CRP

    1) The fat profile: Since supposedly the well fed RS bugs would lower the absorption of sugars and better regulated and metabolise BG levels. And moreover they would produce short chain fatty accids. So I would expect to see the triglicerides going down and hopefully the HDL goiing up.

    2) The serum levels of 25(OH) Vit D - have a lot of influence in the body. And since it is winter - nobody would get the UVB rays. Does the good bugs produce Vit D ? Might they produce more B12? Do they improve the Vit D/B12 absorption.


    3) As a marker for inflamation - would it improve.



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  2. Thanks Vasil. Sorry for the long delay getting back to you. I have about $200 available for extra testing. So there are a few options worth following-up on.

    We supplement D3 about 9 months a year, so that's probably not a going to be a very interesting one. As for a lipid panel and CRP, those seem interesting. Do you know how fast those respond in the human body? With only 6 weeks between before & after do you know if it is even possible for them move in a significant manner?

    Thanks.

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    1. I do not know. Maybe the lipid profile would move most.

      It sounds like your family CRP would be low already so no change is expected.


      Even if not for this experiment - watching those markers would make sense. I've read intresting articles that the "good" bacteria make biofilms and communicate by producing vitamins.


      http://coolinginflammation.blogspot.com/2013/07/vitamin-c-guinea-pigs-limeys-and-gut.html
      http://coolinginflammation.blogspot.com/2012/04/dr-oz-vitamins-biofilms.html

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